Hysingla ER provides 24 hours of continuous hydrocodone delivery

One Hysingla ER tablet a day can deliver your patient's full daily dose of hydrocodone

Hysingla ER is taken once every 24 hours, at the same time each day

Instruct patients to swallow Hysingla ER tablets whole, one tablet at a time, with enough water to ensure complete swallowing immediately after placing in the mouth. Instruct patients not to pre-soak, lick, or otherwise wet the tablet prior to placing in the mouth.

Crushing, chewing, or dissolving Hysingla ER tablets will result in uncontrolled delivery of hydrocodone and can lead to overdose or death.

ER Tablet

Hydrocodone plasma concentrations are maintained over 24 hours

Mean steady-state plasma hydrocodone concentration profile
  • Steady state hydrocodone concentrations were achieved by Day 3 of once-daily dosing with Hysingla ER 30 mg

Pharmacokinetic data do not correlate to clinical effects.

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